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When his fiancée Lucy falls victim to a mysterious illness, Arthur Holmwood turns to a former rival in her affections – Dr John Seward – for help. Seward calls in his mentor, Professor Van Helsing, who quickly uncovers the terrifying truth; the “illness” that afflicts Lucy is in fact a vampire’s curse, and the only cure is a fresh supply of human blood. The discovery of several bodies – each drained of their blood – forces Van Helsing and Seward into a race against time to destroy the curse once and for all.